Ativan vs Xanax: The Duel No One is Winning

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Ativan vs Xanax: The Duel No One is Winning

SAMHSA has found that benzodiazepines in the U.S. are the most abused pharmaceutical drug. Two of the drugs in the “benzo” family are Ativan and Xanax. They are two types of benzodiazepine medications that are available for nearly the same conditions. They come with many of the same risks and users will often abuse them with other substances.

In fact, a TEDS report stated that 95% of people admitted for benzodiazepine dependency abused other substances with it. The Treatment Episode Data Set (TEDS) found that alcohol was frequently abused along with benzodiazepines.

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Xanax (alprazolam) and Ativan (lorazepam) are both a part of the benzodiazepine drug group. Benzos are considered a psychoactive drug. They can be administered as sedatives, muscles relaxants, and tranquilizers. They will both be prescribed to ease patients with the following disorders:

  • Anxiety.
  • Nervous tension.
  • Psychological symptoms of all kinds.
  • They can stop seizures and tremors.
  • Insomnia due to anxiety.

When comparing Xanax and Ativan, there are quite a few similarities but also some differences. So which is the most effective with the least amount of risks?

Xanax vs. Ativan – How are They Similar?

Xanax vs. Ativan – How are They Similar?

Xanax and Ativan share many of the same qualities as well as risks. They have the same potency and both medications will begin working relatively quickly in the body. When it comes to Xanax dosage vs. Ativan dosage, they are both administered in low doses due to their high potency.

Ativan dosage: 0.5-1 mg

Xanax dosage: 0.25-1 mg

Ativan vs. Xanax Prescriptions

Ativan vs. Xanax Prescriptions

The uses of Ativan vs. Xanax differ. Doctors will give them to patients with different disorders. They have been FDA approved for patients of different ages as well. Ativan can be used for patients 12 and over while Xanax isn’t prescribed to patients that are under 18.

Ativan uses:

Ativan dosages are used for patients with anxiety. They can also be used as a preoperative sedative. Ativan is available in a pill or liquid form. The doses are available in 0.5 mg, 1 mg, and 2 mg.

Xanax uses:

Xanax is also given to patients with anxiety. They can additionally help patients who suffer from panic disorder. Xanax is prescribed to adults that are over 18. Xanax comes in Pill, Extended-release, Dissolving tablet, and Liquid form. The doses are available in .25 mg, 0.5 mg, 1 mg, and 2 mg.

Ativan Off-Label Uses

Off-label Ativan use refers to the drug being prescribed for something different than its FDA approved for. Doctors may choose to prescribe it for purposes that have been proven to work but isn’t an approved use. Here’s what Ativan might be prescribed for:

  • For a patient who is irritable.
  • For someone suffering from mania.
  • Someone who experiences recurring seizures.
  • Pre-surgery sedating.
  • Vomiting due to chemotherapy.
  • Subduing severe seizures.
  • Assisting in alcohol withdrawal to prevent delirium tremens.

Xanax Off-Label Uses

Xanax also has some off-label uses. They include:

  • Relief of irritable bowel syndrome.
  • Someone who experiences premenstrual syndrome.
  • Relief of ringing ears.
  • Prevention of tremors.

Action Times Between Ativan vs. Xanax

Action Times Between Ativan vs. Xanax

The action times between Ativan and Xanax are different although they are both short acting benzodiazepines. One of the biggest difference between the two drugs is how long they’re active in your body. Ativan action times are longer.

This means that the medicinal effects will last longer in the body. Xanax action time is less so the person will gain benefits of the medication more quickly. It also takes less time for the drug to peak within the body. Ativan can be detected in urine for up to 6 weeks when it’s used in high doses. Even if a person is using the proper doses, it may be detected in drug screening for up to 7 days.

Ativan vs. Xanax-Peak hours

Ativan-Expected time to peak is between 1-6 hours

Xanax-Expected time to peak is between 1-2 hours

Ativan Half Life Times

Ativan average half life is 14-15 hours

Xanax Half Life Times

Xanax average half life is 11-12 hours.

Doctors will prescribe the smallest Xanax dosage possible. The daily dosage is between 0.5-6mg. The medical industry is cautious of Xanax because of the addiction and withdrawal risks. Usually, the Xanax half life is 9-16 hours, depending on how much the person took. Generally, the drug will be completely out of their system in about 4 days.

Addiction Between Ativan and Xanax Differ

When you chronically take any benzodiazepine, the risk of dependency and addiction are there.  Both Ativan and Xanax are no exception. To avoid uncomfortable or painful withdrawal, you’ll want to taper off the drugs over a period of time. One of the Xanax side effects is that is has a greater potential to be abused in comparison to other benzos. This includes Ativan.

Ativan Benefits for the Short-Term

Ativan Benefits for the Short-Term

Ativan has its benefits for patients who suffer from anxiety and sleeplessness.

Ativan is a CNS depressant that slows down unusual activity in the brain. Through calming the brains’ activity, Ativan helps:

  • Relieve anxiety
  • Relieve restlessness
  • Relieve tension
  • Relieve feelings like irrational fears.

It works well with other antidepressants to help manage anxiety disorders. Antidepressants take some time to become effective. Potentially, it can take weeks. This is where Ativan can be helpful because it staves off anxious feelings until the antidepressants kick in.

Ativan use is primarily to help a person manage anxiety symptoms almost immediately for the short-term. Ativan is less likely to have drug interactions compared to Xanax. If someone has to take several medications, Ativan will be at an advantage over Xanax and other benzo’s.

Risks of Continued Ativan Use

Risks of Continued Ativan Use

In just a few weeks however, the nervous system gets used to Ativan effects. Tolerance to the drug then develops. The user will need higher doses to get to the same place of relaxation and calmness. If the person continues to use Ativan, they can become dependent. This is true for a patient who has taken their Ativan dosage and time frame instructed by their doctor.

The Ativan high can cause people to abuse the drug recreationally. Its tranquilizing effect, which is used to relax someone with anxiety, is the high people are seeking. The Ativan high includes a euphoric feeling when taking larger doses. It can cause adverse effects when mixed with alcohol or other substances. It can cause dizziness and drowsiness, which might be what a user is hoping for from their Ativan high.

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Downfalls of Ativan

Cumulative effects of Ativan use or abuse can cause health problems. It can have an impact on a person’s memory. Ativan can be habit forming so using it as long-term treatment isn’t advised. Ativan is one of the more challenging benzodiazepines to withdraw from. Taking it for long periods of time is especially risky, potentially causing addiction.

For those with alcohol or substance abuse problems, they should not be prescribed Ativan. It can cause serious health problems, which includes falling into a coma or death. People who have taken Ativan for long periods of time say that it gets less effective over time. This can cause people to abuse the drug to obtain the benefits.

Ativan Side Effects

Ativan come with side effects such as

  • Problems with sleeping.
  • Cognitive memory problems.
  • Temporary drowsiness, dizziness, and confusion.
  • Physical and mental exhaustion.

Serious Ativan Side Effects

Serious Ativan Side Effects

Serious Ativan side effects can put people at risk. If a person experiences the following, they should call their doctor immediately:

  • They become confused.
  • As benzodiazepines are a depressant to the CNS, they may become depressed.
  • The depressive feelings can lead to thoughts of suicide or hurting oneself.
  • They may experience hyperactivity.
  • They may become agitated which can turn to hostility.
  • They may experience hallucinations.
  • They may become light-headed which can lead to fainting.

Ativan Risks

The benzo family will produce an increase of central nervous system depressant effects when mixed with other substances. This means that a person can become highly depressed or their brain may function very slowly. It can also cause fatal respiratory depression when combined with CNS depressants. If a person is already depressed and they take Ativan regularly, their condition may worsen. If someone has been diagnosed with a depressive disorder, they shouldn’t be treated with Ativan.

Occurrences of risk include:

  • Taking more Ativan than recommended.
  • Using it for longer than a month.
  • If the patient has a drug abuse history.
  • Long-term use.
  • If the patient mixes with alcohol.

Xanax Benefits

Xanax has proven itself to be effective for relief of short-term anxiety. When Xanax vs. Ativan is compared for the efficacy of managing anxiety, both are similar. Xanax can also be used in conjunction with slower acting antidepressants. Xanax use is effective when used for the short-term until the long-term antidepressant treatment kicks in.

Xanax does what most benzodiazepines do, acts on the nerves to create a calming effect. Its anxiolytic properties comes in immediate or extended release. The main benefit of Xanax is the compressed tablet that helps someone relax from a panic attack immediately. Due to its ability to onset immediately, Xanax is the drug of choice for controlling panic attacks.

Xanax Downfalls

It doesn’t take long before Xanax use begins to reveal negative effects on the person. Medically assisted withdrawal from the drug may be necessary which includes tapering off slowly. If someone uses Xanax for too long, they may even require a supervised detox. Someone with bipolar disorder may find it challenging to sleep if they take Xanax. It can also cause mania or excitability.

Common withdrawal symptoms include:

  • Inability to sleep.
  • Irritable.
  • Extreme anxiety or the onset of panic attacks.
  • Trembling or seizures.
  • Nausea.
  • Heart palpitations.

Risks of Continued Xanax Use

When taking Xanax, the body produces far less GABA. This is the body’s natural calming capabilities. The dependency is swift and it’s not particularly safe to withdraw from benzodiazepines alone. The Xanax high comes with its own risks as well. As with any benzodiazepine, it can offer a nice, sedative high that people are drawn to.

Overdose of Xanax is possible when someone takes more than the recommended dose. It may also occur when someone stops and then restarts using Xanax. Mixing Xanax with other depressants like alcohol or other benzos can be extremely risky, causing death.

Xanax Side Effects

Common Xanax side effects include:

  • Potential tolerance and habit forming tendencies.
  • Can cause slurred speech.
  • Fatigue.
  • A change in sex drive.
  • Respiratory depression which leads to shortness of breath.

Regardless of whether a person follows their Xanax dosage or not, these serious side effects may occur. If someone experiences these symptoms, they should seek out medical assistance:

  • Chronic headaches.
  • Exhaustion.
  • Difficulty concentrating.
  • Dry mouth or an increase in salivation.
  • Inability to sexually perform.
  • Rapid changes in weight.
  • A problem urinating.
  • Skin rashes.
  • Seizures may occur.
  • Depression.
  • Rapid, extreme mood changes.

Comparing Ativan vs. Xanax as Effective Prescription Medications

Both Ativan and Xanax are fast-acting benzodiazepines. This does make them an effective part of anxiety treatment. It also makes both of them risky to take because of the amount of pills needed on a daily basis. This can make both drugs more susceptible to being abused.

Xanax is primarily treated for anxiety disorders and short-term relief of anxieties. Xanax uses also fall into the category of helping with panic disorders that involve agoraphobia (or not). It is also helpful with anxiety that is specifically associated with depression.

Ativan is FDA approved for managing anxiety disorders also. It is only approved as a short-term treatment for up to 4 months. It relieves anxiety symptoms that are associated with depression or stress that is associated with insomnia.

What’s important to point out is that Xanax is approved for panic disorder while Ativan is not. Xanax is more likely to be abused because of its fast acting absorption in to the blood stream. If someone uses Ativan for longer than 4 months, it can be more challenging than Xanax to withdraw from. In fact, it may take assistance from an addiction treatment clinic to help a person abstain. This is because intense withdrawal symptoms like seizures or uncontrollable anxiety may occur. The rebound effect can be difficult to manage.

Dangers of Benzodiazepines in General

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Dangers of Benzodiazepines in General

Statistics make it clear that there is a high use of benzodiazepine abuse. Millions of Americans have gone to the emergency room for recreational benzo use. People are abusing the drug in combination with other substances that can cause adverse effects. The Drug Abuse Warning Network (DAWN) stated that fatalities and addiction admissions have been steadily increasing over the years.

For many that start using Ativan and Xanax, there will be withdrawal symptoms. It’s not always easy to get off these prescription drugs. The body gets a tolerance to them quickly and dependence sets in even if a person follows the doctor’s instructions.

When it comes to Ativan vs. Xanax, they share characteristics that are similar. They both have the ability to be abused, are highly addictive, and come with the same risks. It’s a matter of what type of anxiety the person has and whether it includes panic attacks. Whatever drug a person is prescribed, they should be used as instructed and taken with caution.

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Full Infographic:

Ativan vs Xanax - The Duel No One is Winning

NCBI, Acta Psychiatr Belg. (Dec. 1981) [Clinical comparison between alprazolam and lorazepam. A polycentric study in double blind]. Retrieved from, https://www.ncbi.nlm.nih.gov/pubmed/6125089

NCBI, Pharmacotherapy (April 1984) Long-term comparison of alprazolam, lorazepam and placebo in patients with an anxiety disorder. Retrieved from, https://www.ncbi.nlm.nih.gov/pubmed/6144090NCBI

NCBI, Yale Journal of Biology and Medicine (Sept. 2015) Prescription Sedative Misuse and Abuse. Retrieved from, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553644/

NCBI, Addiction. (Nov. 1994) The benzodiazepine withdrawal syndrome. Retrieved from, https://www.ncbi.nlm.nih.gov/pubmed/7841856

NCBI, Psychopharmacology Berlin. 1995 Mar .Comparison of acute alprazolam (0.25, 0.50 and 1.0 mg) effects versus those of lorazepam 2 mg and placebo on memory in healthy volunteers using laboratory and telephone tests. Retrieved from, https://www.ncbi.nlm.nih.gov/pubmed/7597114

Ativan vs Xanax: The Duel No One is Winning
2.7 (53.52%) 361 votes
2019-07-18T15:13:15+00:00June 1st, 2019|14 Comments

14 Comments

  1. Avatar
    F.B. March 1, 2019 at 6:02 am - Reply

    This is great, clear, concise information! Exactly for what I was looking and presented in an easy to understand method. Sad how we’ve become an infographic society. Anyway, thank you very much! This actually answered all the questions I had regarding each drug. Again, wonderful presentation of information!

    • Avatar
      Evergreen Staff March 6, 2019 at 8:16 pm - Reply

      We are glad you found the information helpful! We wish you nothing but the best as you continue your journey!

    • Avatar
      M. Baker March 31, 2019 at 1:49 am - Reply

      Very good advice. And as someone who takes these meds therapeutically, I can attest this information is true. To those out there, be careful and remember “less is more” in your treatment regimen. Respect your meds and you will reap the most benefit for a fuller and happier life.

  2. Avatar
    Evergreen Staff April 3, 2019 at 6:03 pm - Reply

    Thank you so much for sharing your personal experiences! We wish you all the best!

  3. Avatar
    Danielle April 24, 2019 at 7:15 pm - Reply

    This article is well-written and helpful to me. I am about to try Ativan (was just prescribed for me) and it helps me to understand why my Psych picked it for me over Xanax. It also helps me set goals to take as little as possible, watch for signs of dependence, and not plan on taking it indefinitely! Thank you so much!

    • Avatar
      Evergreen Staff April 25, 2019 at 6:15 pm - Reply

      Glad you found the article helpful! As with any medication, it is always best to watch for dependency signs and only take as needed. We wish you all the best on your journey!

  4. Avatar
    Anthony Harrell April 26, 2019 at 4:10 pm - Reply

    Great information. I am at the front end of an anxiety/panic disorder, and am wanting to make a choice on which medication to use. After 20 very vague articles seemingly written for for the recreational drug user. Finally one that answers the truly clinical questions I had.

    • Avatar
      Evergreen Staff May 15, 2019 at 4:55 pm - Reply

      Glad you enjoyed the article! We wish you all the best on your journey!

  5. Avatar
    LILA GOLDBERG May 8, 2019 at 2:14 am - Reply

    ARTICLE HAD EVERYTHING I WANTED TO KNOW. THANK YOU

    • Avatar
      Evergreen Staff May 15, 2019 at 4:38 pm - Reply

      Glad the article resonated with you!

  6. Avatar
    Jenni May 21, 2019 at 5:43 pm - Reply

    Thanks for the balanced and concise information. I am a therapist, and I’m frustrated with how many of my clients have been given long term prescriptions to take Xanax daily. It is especially problematic for Panic Disorder, where benzodiazepine we makes panic symptoms worse over time. And it is unnecessary. Cognitive Behavior Therapy is extremely effective for Panic Disorder. A few months of CBT therapy and most clients no longer meet the criteria for Panic Disorder diagnosis. Many of my clients stopped xperiencing panic attacks within a month of starting weekly CBT therapy.

    • Avatar
      Evergreen Staff June 3, 2019 at 5:12 pm - Reply

      Thank you for adding your information and continuing this discussion! We are glad you found the article helpful and wish you all the best!

  7. Avatar
    Ariel May 26, 2019 at 11:09 pm - Reply

    Thank you for the information about the medicine it was exactly what I was looking for and will help me get the right one for my condition.

    • Avatar
      Evergreen Staff June 3, 2019 at 5:10 pm - Reply

      Glad you enjoyed the article and found what was best for you!

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